Andrea Bocelli, The Killers, Kacey Musgraves, Elton John, Jennifer Lopez, John Legend, Jennifer Hudson, and many, many more, are all set to take part in the event on 18 April.
Organised by Gaga and Global Citizen, a charitable organisation, the concert will consist of a six-hour pre-show available to stream online, before a two-hour main event airing both online and on television.
The global special has raised $35m (£38m) benefiting healthcare workers and the World Health Organisation.
Here is everything you need to know to watch One World: Together at Home:
True to its name, the concert is airing around the world.
Globally, the event will be available to watch online on several platforms. Amazon Prime Video, Facebook, Instagram, TuneIn, Twitch, Twitter and YouTube will all stream the entire event, meaning both the pre-show and the main concert. That will take place from 2pm ET, or 7pm BST.
Apple will air the concert from 8pm ET, or 1am BST, on Apple Music, Apple TV, and Apple Beats 1.
The EBU is also listed as one of the global broadcasters for the event, with specific times to be determined.
In North America, additional providers will make the concert available on TV and/or online. US viewers can watch the event on TV on ABC, AXS, CBS, Katz Networks, National Geographic, NBC, and Univision from 8-10pm ET.
Tidal will also air the event online from 2-10pm for US viewers. Bein will broadcast the concert from 8pm ET for US and Canadian viewers.
In Europe too, additional providers will air the event.
Viewers in the UK can either tune in via one of the global broadcasters listed above, or catch up on BBC One (either on TV or online) on 19 April from 7:15-9:15pm BST.
For full global listings, visit the event’s page on Global Citizen.