NFL Week 4 Predictions: Our Picks Against the Spread

Chicago Bears (2-1) at Giants (2-1), 1 p.m., Fox

Line: Giants -3.5 | Total: 38.5

The Giants’ two-game win streak came to an abrupt halt, met by the Cowboys’ defense that pressured Daniel Jones a record 23 times and collected five sacks. Adding injury to insult, Giants receiver Sterling Shepard tore his anterior cruciate ligament on the offense’s last play of the game. The Bears are coming off a win despite a poor Week 3 performance from quarterback Justin Fields, who threw two interceptions against the Texans and has not thrown a touchdown pass since the season opener. He should be able to hand the ball off with ease to Khalil Herbert or David Montgomery against the Giants, who give up 5.3 rushing yards per attempt, fifth-most in the league. Pick: Bears +3.5

Jets (1-2) at Pittsburgh Steelers (1-2), 1 p.m., CBS

Line: Steelers -3.5 | Total: 40

The Jets put left tackle George Fant on injured reserve, where he joined two of the team’s other offensive lineman. The timing couldn’t be worse as quarterback Zach Wilson is expected to return to the lineup this week after getting knee surgery to repair a torn meniscus in training camp.

Pittsburgh struggled against the Browns last week, and fans’ calls have grown louder for Coach Mike Tomlin to bench quarterback Mitch Trubisky in favor of the rookie (and Pitt alum) Kenny Pickett. Tomlin is benching the veteran nose tackle Tyson Alualu for Montravius Adams, probably a reaction to Nick Chubb’s running for 113 yards on the Steelers last Thursday night. Adams will line up against an offensive line of Jets bench-warmers. Pick: Steelers -3.5

Arizona Cardinals (1-2) at Carolina Panthers (1-2), 4:05 p.m., Fox

Line: Panthers -2.5 | Total: 43

The Cardinals’ best weapon is their quarterback, who is one of the best rushing quarterbacks in the N.F.L. For some reason, the team hasn’t been letting him scramble and run. His rush attempts are down from 6.3 per game to 4. Carolina is coming off its first win of the season, but its defense still let a banged-up Jameis Winston throw for 353 yards. Pick: Cardinals +2.5

New England Patriots (1-2) at Green Bay Packers (2-1), 4:25 p.m., CBS

Line: Packers -10.5 | Total: 40.5